Product Name:
Macaca Fascicularis Amyloid Beta Peptide 42 (Aβ42) ELISA Kit
Cat.#:
JL52907
Regulatory Status:
Alternative:
Amyloid Beta Peptide 42
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
15.6-1000pg/mL
Sensitivity:
7.3pg/mL
Specificity:
This kit recognizes Macaca fascicularis Aβ42 in samples. No significant cross-reactivity or interference between Macaca fascicularis Aβ42 and analogues was observed.
Sample Type:
Serum;plasma and other biological fluids
Assay Procedure:
Research Area:
Neuroscience
Size & Price: 
Product Datasheets
Instruction: 
| Aβ42
Amyloid beta (Aβ, Abeta or beta-amyloid) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease.The most common isoforms are Aβ40 and Aβ42; the longer form is typically produced by cleavage that occurs in the endoplasmic reticulum, while the shorter form is produced by cleavage in the trans-Golgi network.Amyloid-beta protein 42 is a more effective reductant than amyloid-beta protein 40.
| Repeatability
Intra-assay Precision (Precision within an assay)：CV% < 10%; Inter-assay Precision (Precision between assays)：CV% < 10%| Recovery
The recovery of Macaca fascicularis Aβ42 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.| Sample Type | Range(%) | Average Recovery(%) |
| Serum(n=8) | 84-101 | 95 |
| Plasma(n=8) | 92-106 | 103 |
| Linearity
Samples were spiked with high concentrations of Macaca fascicularis Aβ42 and diluted with Universal Diluent to produce samples with values within the range of the assay.| Serum(n=4) | Plasma(n=4) | ||
| 1 : 2 | Range (%) | 84-95 | 88-95 |
| Average (%) | 91 | 93 | |
| 1 : 4 | Range (%) | 89-102 | 87-108 |
| Average (%) | 94 | 97 |
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